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Anti-ITGA2 Antibody Fab (CAT#: MOM-18251-F(P))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA2 Antibody Fab Fragment MOM-18251-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized Antibody Fab Fragment binds selectively to Human ITGA2, expressed in E. coli
  • Target
  • ITGA2
  • Type
  • Fab Fragment based on Humanized IgG4 - kappa
  • Immunogen
  • Whole human keratinocytes.
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Predicted N terminal
  • H chain: QVQLQES; L Chain: DIVMTQS
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
  • Function
  • collagen binding; protein binding; receptor activity;
  • Synonyms
  • ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49B; integrin alpha-2; CD49b; integrin alpha 2; collagen receptor; VLA-2 subunit alpha; platelet antigen Br; platelet glycoprotein Ia; platelet glycoprotein GPIa; CD49 antigen-like family member B; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; BR; GPIa; VLA-2; VLAA2; BDPLT9;

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